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The role of intracellular calcium phosphate in osteoblast

However, despite their requisite function in building bone and decades of observations describing intracellular calcium phosphate, the precise role osteoblasts play in mediating bone apatite formation remains largely unknown.

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CALCIUM PHOSPHATE STONES: Causes and Prevention Kidney

Idiopathic calcium phosphate stone formers are dual. Most have hydroxyapatite (HA, like bone mineral) as their stone calcium phosphate. Some have brushite (Br, calcium monohydrogen phosphate) in their stones. These latter have more kidney damage than HA CaP stone formers, and are a special high risk group of patients.

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KIDNEY STONE TYPES Kidney Stone Evaluation And Treatment

Much like calcium oxalate, calcium phosphate crystals begin simply as one to one pairings of doubly negative phosphate ions with doubly positive calcium atoms. This initial crystal is named brushite.

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Calcium phosphate uroliths (hydroxyapatite, brushite

and carbonate-apatite. The name carbonate-apatite is derived from the fact that carbonate ion may displace phosphate ion in some uroliths. Less common forms of calcium phosphate include calcium hydrogen phosphate dihydrate (Brushite), tricalcium orthophosphate (Whitlockite), and octacalcium phosphate.

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Calcium Phosphate Scale Next Generation Blog

Jul 19, 2019· Calcium phosphate is a mineral formation, also called apatite, made up of Calcium (Ca), Phosphorus (P), and Oxygen (O). Some variations include Hydrogen (H) and other elements too. Calcium phosphate’s formula looks like (Ca 5 (PO 4) 3). Again, there are variations:

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The role of intracellular calcium phosphate in osteoblast

Osteoblasts create the nano-composite structure of bone by secreting a collagenous extracellular matrix (ECM) on which apatite crystals subsequently form. However, despite their requisite function in building bone and decades of observations describing intracellular calcium phosphate, the precise role osteoblasts play in mediating bone apatite

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Influence of Calcium Phosphate and Apatite Containing

The aim of the present study was to compare the effect of a conventional fluoride preparation and of modern calcium phosphate or apatite containing prophylactic products on initial erosive mineral loss in a combined in situ/in vitro setup. Surface alterations and layer formation were visualized electron-microscopically. 2. Materials and Methods

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Calcium Phosphate Scale Next Generation Blog

Jul 19, 2019· Calcium phosphate is a mineral formation, also called apatite, made up of Calcium (Ca), Phosphorus (P), and Oxygen (O). Some variations include Hydrogen (H) and other elements too. Calcium phosphate’s formula looks like (Ca 5 (PO 4) 3). Again, there are variations: Apatite Ca 5 (PO 4) 3; Hydroxyapatite Ca 10 (PO 4) 6 (OH) 2; Fluorapatite

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Apatite Wikipedia

Apatite is a group of phosphate minerals, usually referring to hydroxyapatite, fluorapatite and chlorapatite, with high concentrations of OH −, F − and Cl − ions, respectively, in the crystal.The formula of the admixture of the three most common endmembers is written as Ca 10 (PO 4) 6 (OH,F,Cl) 2, and the crystal unit cell formulae of the individual minerals are written as Ca 10 (PO 4) 6

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The role of collagen in bone apatite formation in the

Oct 24, 2010· Apatite crystals are found within an amorphous calcium phosphate bed, which can still be seen infiltrating into the fibril through the a-band (inset 1, black arrow). Insets 2–5 show crystals

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Calcium Hydroxyapatite and How to Best Protect Your Bones

Jul 15, 2020· Calcium hydroxyapatite contains the amino acids, phosphate, and other essential minerals that human bones need. Calcium hydroxyapatite’s similarity to the composition of natural bone allows for optimal bioavailability and stability over other calcium phosphate ingredients. The calcium found in calcium hydroxyapatite is superior to other forms

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How are the types of calcium different? The most common

When it comes to calcium supplements, you’ll commonly find calcium phosphate as tricalcium phosphate or microcrystalline hydroxyapatite (MCHC we’ll cover this in just a moment.) Tricalcium phosphate supplements tend to source their calcium from phosphate rock– that’s any rock with a high concentration of phosphate.

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FELINE CALCIUM PHOSPHATE University of Minnesota

Calcium phosphate uroliths (hydroxyapatite, brushite, whitlockite, and octacalcium phosphate) are uncommon in cats. Common conditions associated with these minerals include hypercalcemia, hyperparathyroidism, and dystrophic and ectopic mineralization of vital tissues

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(PDF) The influence of Ca/P ratio on the properties of

Outside this compositional range the powders were biphasic mixtures composed of a calcium phosphate apatite and CaHPO4 (Ca/P < 1.5) or Ca(OH)2 (Ca/P > 1.667). Temperature and pH of synthesis were

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Know your kidney stones ACP Internist

Calcium oxalate is the most common type of stone, seen in 74% of first-time stone formers and 66% of recurrent stone formers. Struvite stones, also called “infection stones” or Mg-NH 4 + carbonate-apatite stones, only form when urease-producing bacteria are present in the upper urinary tract, Dr. Curhan noted. Complete stone removal is

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Osteopontin regulates biomimetic calcium phosphate

Moreover, recent high-resolution measurements of apatite crystallites in bone have shown that individual crystallites are covered by a persistent layer of amorphous calcium phosphate. It is therefore unclear whether non-collagenous proteins can interact with the faces of the mineral crystallites directly and what are the consequences of the

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Kidney Stones: Diagnostic and Treatment Strategies

Calcium stone formation begins with formation of calcium phosphate deposits (Randall plaques) on the external urothelial surface of the papilla. Hence, calcium oxalate stones typically have a small component of calcium phosphate (apatite or brushite). If small particles were not anchored to these plaques, they would simply wash into the urine.

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Phosphate vs Apatite What's the difference? WikiDiff

As nouns the difference between phosphate and apatite is that phosphate is (chemistry) any salt or ester of phosphoric acid while apatite is (mineral) a calcium fluoride phosphate of variable composition, sometimes used in the manufacture of fertilizer. As a verb phosphate is to treat or coat with a

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Calcium Phosphate an overview ScienceDirect Topics

Calcium phosphate, for example, hydroxyl apatite, is a product directly comparable to rock phosphate. Thereby, one has to keep in mind that in practice the kinetics of calcium phosphate precipitation plays a major role than thermodynamic equilibrium considerations. Thus, in most cases, spontaneous precipitation of calcium phosphate from the

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[A study of bone-like apatite formation on calcium

The research of bone-like apatite formation is a great help to understanding the mechanism of osteoinduction. Synthetic porous calcium phosphate ceramics (HA/TCP = 70/30) were implanted intramuscularly in pigs, dogs, rabbits and rats to make a comparative study of the bone-like apatite formation onto the porous HA/TCP ceramics in different animals.

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Calcium Phosphate Scale Next Generation Blog

Jul 19, 2019· Calcium phosphate is a mineral formation, also called apatite, made up of Calcium (Ca), Phosphorus (P), and Oxygen (O). Some variations include Hydrogen (H) and other elements too. Calcium phosphate’s formula looks like (Ca 5 (PO 4) 3). Again, there are variations: Apatite Ca 5 (PO 4) 3; Hydroxyapatite Ca 10 (PO 4) 6 (OH) 2; Fluorapatite

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Apatite Formation on Calcium Phosphate Invert Glasses in

Dec 20, 2004· Calcium phosphate invert glasses, which contain P 2 O 7 2− and PO 4 3− ions, have been prepared via the addition of a small amount of TiO 2.The formation of bonelike calcium phosphate apatite on the surface of the phosphate invert glasses was examined in simulated body fluid (SBF) at a temperature of 37°C.

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The role of collagen in bone apatite formation in the

Oct 24, 2010· Apatite crystals are found within an amorphous calcium phosphate bed, which can still be seen infiltrating into the fibril through the a-band (inset 1, black arrow). Insets 2–5 show crystals

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Phosphate vs Apatite What's the difference? WikiDiff

As nouns the difference between phosphate and apatite is that phosphate is (chemistry) any salt or ester of phosphoric acid while apatite is (mineral) a calcium fluoride phosphate of variable composition, sometimes used in the manufacture of fertilizer. As a verb phosphate is to treat or coat with a

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(PDF) The influence of Ca/P ratio on the properties of

Outside this compositional range the powders were biphasic mixtures composed of a calcium phosphate apatite and CaHPO4 (Ca/P < 1.5) or Ca(OH)2 (Ca/P > 1.667). Temperature and pH of synthesis were

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Calcium phosphate kidney stones Nutrition, deficiency

Kidney stones (renal calculi) of calcium phosphate (CaP) and those calculi containing greater amounts of phosphate are to be thoroughly investigated for the underlying medical cause. The most important calcium and PO4 3-involved renal stones are carbonate apatite, hydroxyapatite, and brushite. The struvite calculi are formed of magnesium

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What Is Calcium Hydroxyapatite? (with pictures)

Feb 03, 2021· Andy Josiah Date: February 03, 2021 In teeth, calcium hydroxyapatite can be found in the enamel and the calcified dentin.. Calcium hydroxyapatite, or simply hydroxyapatite, is a mineral that belongs to a group of phosphate minerals known as apatites. It is usually identified with the teeth and bones of humans. In fact, this mineral is a major component of these structures.

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Remedies for The 5 Most Common Types of Kidney Stones

Calcium phosphate stones can be further broken down into two additional types: brushite, which do not break easily and as a result don’t respond well to shock wave treatment, and hydroxyapatite, which can plug the kidneys and damage their cells.

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Know your kidney stones ACP Internist

Calcium oxalate is the most common type of stone, seen in 74% of first-time stone formers and 66% of recurrent stone formers. Struvite stones, also called “infection stones” or Mg-NH 4 + carbonate-apatite stones, only form when urease-producing bacteria are present in the upper urinary tract, Dr. Curhan noted. Complete stone removal is

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Apatite Formation from Amorphous Calcium Phosphate and

The speciation of phosphate was controlled by pH to favor HPO 4 2−. In a carbonate free system, the reaction produces anisotropic apatite crystallites with large aspect ratios. The first formed crystallites are highly calcium deficient and hydrogen phosphate rich, consistent with thin octacalcium phosphate (OCP)‐like needles.

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The role of intracellular calcium phosphate in osteoblast

The role of intracellular calcium phosphate in osteoblast-mediated bone apatite formation Suwimon Boonrungsimana, Eileen Gentlemana,b,c, Raffaella Carzanigad, Nicholas D. Evansa,b,1, David W. McComba,e, Alexandra E. Portera,2, and Molly M. Stevensa,b,f,2 Departments of aMaterials and fBioengineering, bInstitute of Biomedical Engineering, and dElectron Microscopy Centre, Division of

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UpToDate

The two forms of calcium phosphate include apatite (sometimes reported as carbonate apatite), which is the crystal type found in bone, or calcium hydrogen phosphate (brushite); the frequency of apatite is much greater than brushite. Calcium phosphate crystals in

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Hydroxyapatite :: properties, uses and applications

Hydroxyapatite (HAp) is a calcium phosphate similar to the human hard tissues in morphology and composition 1.Particularly, it has a hexagonal structure 2, 3 and a stoichiometric Ca/P ratio of 1.67, which is identical to bone apatite 2, 4, 5.. An important characteristic of hydroxyapatite is its stability when compared to other calcium phosphates.